Sunday, March 31, 2013

Son of pro wrestler Ric Flair found dead

(AP) ? Authorities say the son of professional wrestler Ric Flair has been found dead in a North Carolina hotel room.

Charlotte-Mecklenburg police says officers were called to a hotel on the city's south side around 10:30 a.m. Friday. When they arrived, they found the body of 25-year-old Reid Fliehr, who also was a wrestler.

A statement from police says there are no signs of foul play, and that the cause of death will be determined by the medical examiner's office.

Flair's agent released a statement Friday describing Reid as "an incredible son, brother, friend, and professional wrestler."

Ric Flair's real name is Richard Morgan Flair. The peroxide-blond wrestled for some 40 years and also was known as The Nature Boy.

The 64-year-old won many pro wrestling titles including in the WWE.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-03-29-Ric%20Flair's%20Son/id-82004d20dd48493584a71add69ece622

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Facebook expected to introduce themed Android OS, HTC handset next week

HTC's Status may not have been a tremendous hit, but it looks like Facebook hasn't severed its ties with the smartphone maker just yet. According to TechCrunch and New York Times sources, April 4th's "Come See Our New Home on Android" event is set to feature an HTC smartphone with a custom, Facebook-centric OS. It's perhaps the next best thing to a phone designed and manufactured by Facebook, but instead, HTC will be tasked with creating the hardware. The integration is expected to run deep, however -- when you power on the device, a Facebook home screen is what you'll see first. Additionally, the device's camera and messaging apps will default to Facebook, according to the New York Times report. Hardware specifications have yet to be revealed, but software will clearly be the focus here. Tune in at 1PM EST next Thursday for our liveblog, direct from Facebook HQ.

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Source: The New York Times, TechCrunch

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Drones over America: How unmanned fliers are already helping cops

It was getting dark, and the sheriff of Nelson County, N.D., was in a standoff with a family of suspected cattle rustlers. They were armed, and the last thing anybody wanted was a shoot out.

U.S. Customs and Border Protection, which monitors police radio chatter, offered to help. Their Predator was flying back to its roost at the Grand Forks Air Force base and could provide aerial support. Did the sheriff want the assist?

Yep.

"We were able to detect that one of the sons was sitting at the end of the driveway with a gun. We also knew that there were small children involved," Sheriff Kelly Janke told NBC News, remembering that tricky encounter in the early summer of 2011. "Someone would have gotten seriously injured if we had gone in on the farm that night." He decided to wait.

The next day, the drone gave them an edge again by helping them choose the safest moment to make a move. "We were able to surprise them ? took them into custody," Janke said. They also collected six stolen cows.

Rodney Brossart, the arrested farmer, sued the state, in part because of the cop's use of a drone. But a district judge ruled that the Predator's service was not untoward.

When advocates express concern about government drones threatening people's privacy, the Brossart case is one they bring up. It's one of the first instances of a flying robot doing a cop's dirty work, and this kind of intervention is likely to be more and more commonplace, as the FAA fulfills a congressional mandate to increase its granting of drone permits ? certificates of authorization, or COAs.

Cops and flying robots
At the moment, there are only 327 active COAs, all held by these organizations, and all for unarmed crafts, of course. A tiny sliver of these permits are in the hands of law enforcement agencies, and from them, we're seeing the first glimpses of drone use in policing and emergency response.

"The FAA has approved us to cover a 16-county area," Sheriff Bob Rost of Grand Forks County, N.D., said of their COA. "To look for missing children, to look for escaped criminals and in the case of emergencies." In the spring, they will use two mini-copter drones ? a trusty DraganFlyer X6 and an AeroVironment Qube ? to check on flooded farms.

The police department in Arlington, Texas, also recently got FAA clearance to fly their drones after two years of testing. The two battery-powered Leptron Avenger helicopter drones won't be used for high-speed chases or routine patrol, the department explains. In fact, the crafts will be driven in a truck to where they're needed, and when they're launched to scope out incidents, local air traffic control will be informed.

In Mesa County, Colo., the police department has used drones to find missing people, do an aerial landfill survey and help out firefighters at a burning church. For them, it's seen as a cost-cutting technology.

"It's the Wal-Mart version of what we'd normally get at Saks Fifth Avenue," said Benjamin Miller, who leads the drones program in Mesa County, comparing drones to manned helicopters that would otherwise give police officers help from the sky.

In Seattle, the police department received an FAA permit ? but had to give back its drones when the mayor banned their use, following protests in October 2012.

Protests and red tape
"Hasn't anyone heard of George Orwell's '1984'?" the Seattle Times quoted a protester as saying. "This is the militarization of our streets and now the air above us."

Protesters, not just in Seattle, seek more legal definition of what a drone can or can't do, and debate whether or not current laws sufficiently protect citizens from unauthorized surveillance and other abuses.

New York City mayor Michael Bloomberg thinks of police drones as an inevitability ? "We're going to have them," he recently said in a radio interview ? while those on the police (and drone) side say the fears are unfounded.

"This hysteria of [a drone] hovering outside your backyard taking a video of you smoking a joint, it's just that ? hysteria," said Al Frazier, an ex-cop from Los Angeles who is now an assistant professor of aeronautics at the University of North Dakota, and a deputy at the Grand Forks sheriff's office.

The reason the sky isn't lousy with drones already mostly has to do with red tape. The FAA's highly restricted drone application for government agencies is supposed to take about 60 days, though unofficially, we're told it's much longer. COAs are also very strict about where, when and by whom a drone is flown.

"I think there are many agencies who would like to use [drones] for public good, but they're stymied by the process," Frazier said.

That's likely to change ? and soon. Last February, Obama signed a mandate that encourages the FAA to let civil and commercial drones join the airspace by 2015. This will take new regulations from the FAA for safe commercial drone flight, and it may take some convincing of local anti-drone activists (who sometimes don't differentiate between drones great and small). It may even require the passing of a few new privacy laws.

Folks like Frazier and Miller don't see the permit process getting easier any time soon but eventually ? inevitably ? and for better or worse, your local police department will get its drone.

Nidhi Subbaraman writes about technology and science. Follow her on Twitter and Google+.

Related:

The drones are coming ... but our laws aren't ready

Anticipating domestic boom, colleges rev up drone piloting programs

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2a26de47/l/0L0Snbcnews0N0Ctechnology0Ctechnolog0Cdrones0Eover0Eamerica0Ehow0Eunmanned0Efliers0Eare0Ealready0Ehelping0Ecops0E1C9135554/story01.htm

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Argentina challenges U.S. court with bond plan

By Nate Raymond and Hugh Bronstein

NEW YORK/BUENOS AIRES (Reuters) - Argentina challenged a U.S. court over the weekend by proposing that "holdout" bond investors be repaid only about one sixth the money federal judges hearing the case say they are owed, setting the stage for a legal showdown in New York.

The terms offered by Argentina are the same as those accepted by bondholders who chose to participate in the country's 2010 sovereign bond restructuring. The holdouts rejected that restructuring and are holding out for full repayment.

Aside from the implications the case has for Argentina's finances, it could also have wide ramifications for the way future sovereign restructurings are carried around the world.

Argentina defaulted on $100 billion in sovereign debt in 2002 at the height of a financial crisis in Latin America's third largest economy. The bonds now under dispute were issued in New York, which is why the case is being heard in U.S. court.

Elliott Management affiliate NML Capital Ltd, one of the lead plaintiffs, has said that it will not accept 2010 terms They and other holdouts are sure to argue that Argentina's proposal does not respond to the court's request.

"The court said 'You owe the holdouts $1.3 billion. Tell us how you are going to pay that to them,'" said Josh Rosner, managing director at research firm Graham Fisher & Co in New York.

"Instead of answering how they will pay the full amount, Argentina responded with a plan for paying a much smaller amount," he said. "Argentina is flirting with technical default, which would take a serious toll its economy."

The specter of technical defaults comes from the fact that a U.S. District Court in New York has said that until the holdouts start getting paid, Argentina cannot make payments to holders of the restructured bonds.

Elliott stands currently to receive $720 million from Argentina following a New York judge's order in November, according to Argentina.

But the bonds NML could take had a market value of just $186.8 million before a major decision in the case last October favoring the holdouts, or $120.6 million as of March 1, the filing said. Argentina estimates NML paid about $48.7 million in 2008 for its stake in the bonds.

"The Republic is prepared to fulfill the terms of this proposal promptly upon Order by the Court by submitting a bill to Congress that ensures its timely implementation," Jonathan Blackman, Argentina's U.S. lawyer, wrote.

Around 92 percent of Argentina's defaulted bonds were restructured in 2005 and 2010, with bondholders receiving 25 cents to 29 cents on the dollar.

But holdouts led by NML Capital and Aurelius Capital Management have fought for years for full payment. Argentina calls these funds "vultures."

In October, the 2nd Circuit upheld a trial judge's ruling by finding Argentina had violated a so-called pari passu clause in its bond documents requiring it to treat creditors equally.

U.S. District Judge Thomas Griesa in Manhattan subsequently ordered Argentina in November to pay the $1.33 billion owed to the bondholders into an escrow account by the time of its next interest payment to holders of the exchanged debt.

The 2nd Circuit heard an appeal of that order on February 27. Two days later, it directed Argentina to provide details of "the precise terms of any alternative payment formula and schedule to which it is prepared to commit."

BOND OPTIONS

In its 22-page submission late on Friday, Argentina said that under a so-called par bond option, the bondholders would receive new bonds due in 2038 with the same nominal face value of their current bonds. They would pay 2.5 percent to 5.25 percent a year, Argentina said.

Bondholders would also receive an immediate cash payment similar to what it provided under the 2010 debt swap, Argentina said. And they would receive derivative instruments that provide payments when the country's gross domestic product exceeds 3 percent a year.

The par option is restricted to small investors, unlike the discount option, the more applicable fit for big investors like NML and Aurelius.

Under the discount proposal, holdouts could receive new discount bonds due in 2033 that pay 8.28 percent annually. Argentina said the holdouts would also receive past due interest since 2003 in the form of bonds due in 2017 paying 8.75 percent a year, and GDP-linked derivative units.

Blackman, Argentina's lawyer, wrote that the proposal, unlike what he called the "100 cents on the dollar immediately" formula Griesa adopted, "is consistent with the pari passu clause, longstanding principles of equity, and the Republic's capacity to pay."

It was unclear on Saturday how the court might view Argentina's proposals. The same three-judge panel had said in October, though, that the holdouts "were completely within their rights" to reject prior debt swap offers.

Euginio Bruno, a lawyer and bond restructuring expert with the law firm Estudio Garrido Abogados in Buenos Aires, said the government's Friday proposal "was within expectations, considering the legal constraints on offering anything better than the terms of the 2010 restructuring."

Argentina has a "lock law" that keeps new governments from improving the terms of previous restructurings.

Earlier in the week, the holdouts scored a victory over Argentina when the 2nd Circuit denied a full court review of its October ruling on the equal treatment provision.

The United States had backed Argentina in seeking the review, contending the 2nd Circuit's decision ran "counter to longstanding U.S. efforts to promote orderly restructuring of sovereign debt.

Argentina and holders of its restructured bonds say granting the holdouts 100 cents on the dollar could complicate future sovereign restructurings around the world.

Argentine Vice President Amado Boudou repeated on Saturday that Argentina would continue repaying investors who participated in the restructuring no matter how the U.S. court case is resolved.

"One way or another, Argentina will pay," he said.

The case is NML Capital Ltd et al v. Republic of Argentina, 2nd U.S. Circuit Court of Appeals, No. 12-105.

(Reporting by Nate Raymond; Additional reporting by Helen Popper, Alejandro Lifschitz and Guido Nejamkis in Buenos Aires; Editing by Todd Eastham, Will Dunham and Eric Beech)

Source: http://news.yahoo.com/argentina-challenges-u-court-bond-plan-011959470--sector.html

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Saturday, March 30, 2013

Chinese Regulations On WMPs - Business Insider

The Chinese stock market took a hit Thursday after its banking regulator issued new regulations to tighten control over banks' wealth management products (WMPs).?

WMPs are essentially a pool of securities (trust products, bonds, stock funds) that have yield that is on average 2 percentage points higher than bank deposits. They are sold as low-risk investments but often are not so.?

With a dearth of investment alternatives, WMPs have grown incredibly popular in China in the past few years, reaching 13 trillion yuan ($2.1 trillion) at the end of 2012, a 50 percent year-over-year increase, according to Fitch.

WMPs have been creating risks in the banking sector and some have called it "ponzi finance":

To lower these risks, the China Banking Regulatory Commission (CBRC) announced three key regulations to monitor WMPs (via Societe Generale's Wei Yao):

  1. "WMPs have to be managed product by product with matching assets, separate accounting and book-keeping." If banks fail to do this they will be prevented from issuing new WMPs.
  2. "For outstanding WMPs that have not met the requirement above, they should be treated like regular commercial loans in terms of loss provisions and risk weights by end-2013."
  3. "For each bank, the amount of WMPs invested in debt instruments that are not traded on exchanges cannot exceed 35% of the bank?s total outstanding of WMPs or 4% of its total asset, whichever is lower. Such debt instruments include, but are not limited to, trust loans, entrust liabilities, bankers? acceptances, account receivables, and equity investment with buy-back clauses."

Yao however thinks banks have been preparing for this, and writes that the new policy isn't intended to "devastate banks, but to cap future risks."

Source: http://www.businessinsider.com/chinese-regulations-on-wmps-2013-3

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If cable companies said true things

The saddest part of this video by Extremely Decent Films [NSFW-L] isn't that it's true, or that it's supported by our governments, or that it's merely representative of many anti-consumer media and technology infrastructure oligopolies, but that we tolerate it to exist.

Does this sound like your cable company? Your cell carrier? When did that become okay?

Source: Extremely Decent Films via The Loop, thanks Anthony!



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Pope's foot-washing final blow for traditionalists

VATICAN CITY (AP) ? Pope Francis has won over many hearts and minds with his simple style and focus on serving the world's poorest, but he has devastated traditionalist Catholics who adored his predecessor, Benedict XVI, for restoring much of the traditional pomp to the papacy.

Francis' decision to disregard church law and wash the feet of two girls ? a Serbian Muslim and an Italian Catholic ? during a Holy Thursday ritual has become something of the final straw, evidence that Francis has little or no interest in one of the key priorities of Benedict's papacy: reviving the pre-Vatican II traditions of the Catholic Church.

One of the most-read traditionalist blogs, "Rorate Caeli," reacted to the foot-washing ceremony by declaring the death of Benedict's eight-year project to correct what he considered the botched interpretations of the Second Vatican Council's modernizing reforms.

"The official end of the reform of the reform ? by example," ''Rorate Caeli" lamented in its report on Francis' Holy Thursday ritual.

A like-minded commentator in Francis' native Argentina, Marcelo Gonzalez at International Catholic Panorama, reacted to Francis' election with this phrase: "The Horror." Gonzalez's beef? While serving as Cardinal Jorge Mario Bergoglio, Francis' efforts to revive the old Latin Mass so dear to Benedict and traditionalists were "non-existent."

The night he was chosen pope, March 13, Francis emerged from the loggia of St. Peter's Basilica without the ermine-rimmed red velvet cape, or mozzetta, used by popes past for official duties, wearing instead the simple white cassock of the papacy.

He also received the cardinals' pledges of obedience after his election not from a chair on a pedestal as popes normally do but rather standing, on their same level. In the days since, he has called for "intensified" dialogue with Islam ? a gesture that rankles some traditionalists because they view interfaith dialogue as a sign of religious relativism.

This year's Good Friday procession at Rome's Colosseum, which re-enacts Jesus Christ's crucifixion, was dedicated to the plight of Mideast Christians, with prayers calling for an end to "violent fundamentalism."

Francis, however, chose to stress Christians' positive relations with Muslims in brief remarks the end of the ceremony. He recalled Benedict's 2012 visit to Lebanon when "we saw the beauty and the strong bond of communion joining Christians together in that land and the friendship of our Muslim brothers and sisters and so many others."

Francis also raised traditional eyebrows when he refused the golden pectoral cross offered to him right after his election by Monsignor Guido Marini, the Vatican's liturgy guru who under Benedict became the symbol of Benedict's effort to restore the Gregorian chant and heavy silk brocaded vestments of the pre-Vatican II liturgy to papal Masses.

Marini has gamely stayed by Francis' side as the new pope puts his own stamp on Vatican Masses with no-nonsense vestments and easy off-the-cuff homilies. But there is widespread expectation that Francis will soon name a new master of liturgical ceremonies more in line with his priorities of bringing the church and its message of love and service to ordinary people without the "high church" trappings of his predecessor.

There were certainly none of those trappings on display Thursday at the Casal del Marmo juvenile detention facility in Rome, where the 76-year-old Francis got down on his knees and to wash the feet of 12 inmates, two of them women. The rite re-enacts Jesus' washing of the feet of his 12 apostles during the Last Supper before his crucifixion, a sign of his love and service to them.

The church's liturgical law holds that only men can participate in the rite, given that Jesus' apostles were all male. Priests and bishops have routinely petitioned for exemptions to include women, but the law is clear.

Francis, however, is the church's chief lawmaker, so in theory he can do whatever he wants.

"The pope does not need anybody's permission to make exceptions to how ecclesiastical law relates to him," noted conservative columnist Jimmy Akin in the National Catholic Register. But Akin echoed concerns raised by canon lawyer Edward Peters, an adviser to the Vatican's high court, that Francis was setting a "questionable example" by simply ignoring the church's own rules.

"People naturally imitate their leader. That's the whole point behind Jesus washing the disciples' feet. He was explicitly and intentionally setting an example for them," he said. "Pope Francis knows that he is setting an example."

The inclusion of women in the rite is problematic for some because it could be seen as an opening of sorts to women's ordination. The Catholic Church restricts the priesthood to men, arguing that Jesus and his 12 apostles were male.

Francis is clearly opposed to women's ordination. But by washing the feet of women, he jolted traditionalists who for years have been unbending in insisting that the ritual is for men only and proudly holding up as evidence documentation from the Vatican's liturgy office saying so.

"If someone is washing the feet of any females ... he is in violation of the Holy Thursday rubrics," Peters wrote in a 2006 article that he reposted earlier this month on his blog.

In the face of the pope doing that very thing, Peters ? like many conservative and traditionalist commentators ? have found themselves trying to put the best face on a situation they don't like lest they be openly voicing dissent with the pope.

By Thursday evening, Peters was saying that Francis had merely "disregarded" the law ? not violated it.

The Rev. John Zuhlsdorf, a traditionalist blogger who has never shied from picking fights with priests, bishops or cardinals when it concerns liturgical abuses, had to measure his comments when the purported abuser was the pope himself.

"Before liberals and traditionalists both have a spittle-flecked nutty, each for their own reasons, try to figure out what he is trying to do," Zuhlsdorf wrote.

But, in characteristic form, he added: "What liberals forget in their present crowing is that even as Francis makes himself ? and the church ? more popular by projecting (a) compassionate image, he will simultaneously make it harder for them to criticize him when he reaffirms the doctrinal points they want him to overturn."

One of the key barometers of how traditionalists view Francis concerns his take on the pre-Vatican II Latin Mass. The Second Vatican Council, the 1962-65 meetings that brought the church into the modern world, allowed the celebration of the Mass in the vernacular rather than Latin. In the decades that followed, the so-called Tridentine Rite fell out of use almost entirely.

Traditionalist Catholics who were attached to the old rite blame many of the ills afflicting the Catholic Church today ? a drop in priestly vocations, empty pews in Europe and beyond ? on the liturgical abuses that they say have proliferated with the celebration of the new form of Mass.

In a bid to reach out to them, Benedict in 2007 relaxed restrictions on celebrating the old Latin Mass. The move was aimed also at reconciling with a group of schismatic traditionalists, the Society of St. Pius X, who split from Rome precisely over the Vatican II reforms, in particular its call for Mass in the vernacular and outreach to other religions, especially Judaism and Islam.

Benedict took extraordinary measures to bring the society back under Rome's wing during his pontificate, but negotiations stalled.

The society has understandably reacted coolly to Francis' election, reminding the pope that his namesake, St. Francis of Assisi, was told by Christ to go and "rebuild my church." For the society, that means rebuilding it in a pre-Vatican II vision.

The head of the society for South America, the Rev. Christian Bouchacourt, was less than generous in his assessment of Francis.

"He cultivates a militant humility, but can prove humiliating for the church," Bouchacourt said in a recent article, criticizing the "dilapidated" state of the clergy in Buenos Aires and the "disaster" of its seminary. "With him, we risk to see once again the masses of Paul VI's pontificate, a far cry from Benedict XVI's efforts to restore to their honor the worthy liturgical ceremonies."

___

Follow Nicole Winfield at www.twitter.com/nwinfield

Source: http://news.yahoo.com/popes-foot-washing-final-blow-traditionalists-204320747.html

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No end to Italy deadlock despite president's efforts

By James Mackenzie and Barry Moody

ROME (Reuters) - Italy remained in political deadlock on Friday after a new round of talks led by President Giorgio Napolitano failed to break the stalemate created by elections last month that left no group able to form a government alone.

Napolitano, 87, conducted a swift round of talks with the three main forces in parliament on Friday after the failure of a week of efforts by center-left leader Pier Luigi Bersani to win support for a new government.

But all the parties remained in the same entrenched positions they have occupied since the February 24-25 election, with no sign of movement from any of them.

Bersani won the largest share of the vote in the election but fell short of a majority in parliament.

The third biggest force, Beppe Grillo's populist 5-Star Movement, which holds the balance of power, on Friday again rejected backing a Bersani government or any administration not led by them.

The center-left in turn reiterated that it would not enter a coalition with Berlusconi, which the 76-year-old billionaire media magnate said after his talks with Napolitano was the only way out of the crisis short of a snap new election.

Bersani's deputy, Enrico Letta, said after meeting Napolitano that a coalition with Berlusconi's center-right, "would not be the choice of change the country has asked for."

Berlusconi and 5-Star both ruled out backing a technocrat government like the one led by outgoing Prime Minister Mario Monti, whom they both blame for pushing Italy into recession.

This had been seen as a possible alternative way to give Italy the government it needs to address a deep economic crisis.

"Our position has not changed. We expressed it with absolute clarity to the president," Berlusconi told reporters after the meeting with Napolitano.

Grillo on Friday scornfully rejected any idea of giving support for a government not led by his movement.

"Give them a vote of confidence? Those are swear words in the mouths of people like them," Grillo said in a live video broadcast on his popular blog. "They should all just go home."

Bersani says Berlusconi is untrustworthy and also rejects the latter's demand to nominate a successor to Napolitano, whose mandate expires in May.

PRESIDENT'S OPTIONS LIMITED

The refusal by Berlusconi and his allies in the Northern League, as well as Grillo, to back a technocrat government reduces Napolitano's options greatly and makes it much less likely that an independent figure will be able to lead a non-political administration.

"We were against the Monti government and if there is to be another government of that type it's a thousand times better to have new elections," League leader Roberto Maroni said.

The political gridlock has fed growing worries about Italy's ability to confront a prolonged economic crisis that has left it in deep recession for more than a year, with a 2-trillion-euro ($2.6-trillion) public debt and record unemployment, especially among the young.

Rumors have been circulating for days that ratings agency Moody's is preparing to cut its rating on Italy's sovereign debt, which is already only two notches above "junk" grade, partly due to the uncertain political outlook.

Napolitano has made clear that he does not want Italy to go back to new elections immediately, not least because the widely criticized election law is likely to just repeat the deadlock.

He made no announcement after the end of the talks on Friday and officials said he was considering his options. After the failure of the latest round of talks it is not clear what he can do to avoid a quick return to the polls.

Many are already preparing to vote again, with Berlusconi's center-right confident that the momentum created by his surge towards the end of the last campaign will continue.

A poll by the SWG company on Friday showed the center-right had pushed Bersani's bloc into second place since the vote.

(Additional reporting by Naomi O'Leary; Editing by Barry Moody and Michael Roddy)

Source: http://news.yahoo.com/italys-president-seeks-way-political-deadlock-091517168.html

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Researchers show stem cell fate depends on 'grip'

Friday, March 29, 2013

The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.

A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.

The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen.

Their study was published in the journal Nature Materials.

Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been done in three dimensions. Three-dimensional environments, or matrices, for stems cells have mostly been treated as simple scaffolding, rather than as a signal that influences the cells' development.

Burdick and his colleagues were interested in how these three-dimensional matrices impact mechanotransduction, which is how the cell takes information about its physical environment and translates that to chemical signaling.

"We're trying to understand how material signals can dictate stem cell response," Burdick said. "Rather than considering the material as an inert structure, it's really guiding stem cell fate and differentiation ? what kind of cells they will turn into."

The mesenchymal stem cells the researchers studied are found in bone marrow and can develop into several cell types: osteoblasts, which are found in bone; chondrocytes, which are found in cartilage; and adipocytes, which are found in fat.

The researchers cultured them in water-swollen polymer networks known as hydrogels, which share some similarities with the environments stem cells naturally grow in. These materials are generally soft and flexible ? contact lenses, for example, are a type of hydrogel ? but can vary in density and stiffness depending on the type and quantity of the bonds between the polymers. In this case, the researchers used covalently cross-linked gels, which contain irreversible chemical bonds.

When seeded on top of two-dimensional covalently cross-linked gels, mesenchymal stem cells spread and pulled on the material differently depending on how stiff it was. Critically, the mechanics guide cell fate, or the type of cells they differentiate it into. A softer environment would produce more fat-like cells and a stiffer environment, where the cells can pull on the gel harder, would produce more bone-like cells.

However, when the researchers put mesenchymal stem cells inside three-dimensional hydrogels of varying stiffness, they didn't see these kinds of changes.

"In most covalently cross-linked gels, the cells can't spread into the matrix because they can't degrade the bonds ? they all become fat cells," Burdick said. "That tells us that in 3D covalent gels the cells don't translate the mechanical information the same way they do in a 2D system."

To test this, the researchers changed the chemistry of their hydrogels so that the polymer chains were connected by a peptide that the cells could naturally degrade. They hypothesized that, as the cells spread, they would be able to get a better grip on their surrounding environment and thus be more likely to turn into bone-like cells.

In order to determine how well the cells were pulling on their environment, the researchers used a technique developed by Chen's lab called 3D traction force microscopy. This technique involves seeding the gel with microscopic beads, then tracking their location before and after a cell is removed.

"Because the gel is elastic and will relax back into its original position when you remove the cells," Chen said, "you can quantify how much the cells are pulling on the gel based on how much and which way it springs back after the cell is removed."

The results showed that the stem cells' differentiation into bone-like cells was aided by their ability to better anchor themselves into the growth environment.

"With our original experiment, we observed that the cells essentially didn't pull on the gel. They adhered to it and were viable, but we did not see bead displacement. They couldn't get a grip," Burdick said. "When we put the cells into a gel where they could degrade the bonds, we saw them spread into the matrix and deform it, displacing the beads."

As an additional test, the researchers synthesized another hydrogel. This one had the same covalent bonds that the stem cells could naturally degrade and spread through but also another type of bond that could form when exposed to light. They let the stem cells spread as before, but at the point the cells would begin to differentiate ? about a week after they were first encapsulated ? the researchers further "set" the gel by exposing it to light, forming new bonds the cells couldn't degrade.

"When we introduced these cross-links so they could no longer degrade the matrix, we saw an increase toward fat-like cells, even after letting them spread," Burdick said. "This further supports the idea that continuous degradation is needed for the cells to sense the material properties of their environment and transduce that into differentiation signals."

Burdick and his colleagues see these results as helping develop a better fundamental understanding of how to engineer tissues using stem cells.

"This is a model system for showing how the microenvironment can influence the fate of the cells," Burdick said.

###

University of Pennsylvania: http://www.upenn.edu/pennnews

Thanks to University of Pennsylvania for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 26 time(s).

Source: http://www.labspaces.net/127524/Researchers_show_stem_cell_fate_depends_on__grip__

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Easter Holidays in Poynton

Easter might just be our favourite break of the year and we?re hoping to get spring sprung by getting out and about with the kids. You won?t have to go far?.Here are some things to do in/ nearby to Poynton?.

Old Time Fair at Brookside Garden Centre, on 29 March 2013 ? 01 April 2013 An Old Time Fair will be at Brookside Garden Centre this Easter on 29th, 30th March and 1st April (closed Easter Sunday).? For further information, please contact the garden centre.

FREE Easter Egg Hunt at Woodford Garden Centre, on 29 March 2013 ? 07 April 2013 Join in the fun this Springtime?FREE Easter Egg Hunt at Woodford Garden Centre. Every correct entry recieves a chocolate lolly. Fri 29th ? Sun 7th April 11am-4pm.

Annual Easter Egg Hunt, Bramhall Village, on 23 March 2013 ? 06 April 2013
Starting on March 23rd and running until 6th April, children in Bramhall can take part in an Easter Egg Hunt organised by independent retailers in the village. ?The 15 participating stores will all have a poster in the window and a map showing all the local shops in which an egg is hidden. Every egg has a letter on it, which the child will need to write down. They?ll also get a sticker to prove they?ve found it. The letters will spell out a simple phrase, which will win the child his/her Easter Egg prize, collectable at A Sweet Thought.

Easter Egg Hunt at St. Paul?s Community Room, on 29 March 2013 ? 29 March 2013
Come and join us for some Eggcelent Family Fun! From 11am-1pm. ?2 / child (Max ?5/family) Preschool & Primary age egg hunts & quiz. Cryptic Code Cracking Hunt for KS2 children. Refreshments & Hot Cross Buns available. Don?t forget your basket! (Organised by Friends of St. Paul?s).

Lambing Season at Blaze Farm, on 29 March 2013 ? 12 April 2013
Watch lambing at Easter at Blaze Farm, Wildboarclough. Lambing season takes place over Easter every year at Blaze Farm.? Watch our flock of sheep lambing from the viewing gallery. ?1 admission to the shed. Open 10am-5.30pm, Tues-Sun & Bank Holidays. Follow this link? for directions.

Easter Bunny Trail, Hatworks, Stockport 1100-1600hrs, on 29 March 2013 ? 31 March 2013
Visit Hat Works this bank holiday weekend and take part in our Easter bunny trail, you never know, you might just win a prize! Suitable for all ages 11am ? 4pm Free. Just drop in Contact: 0161 474 2399

Paper Hat Making, Hatworks, Stockport 1100-1600hrs, on 29 March 2013 ? 31 March 2013
Visit Hat Works this Bank Holiday and get the chance to decorate your very own hat. Pick up your pack of craft materials from reception, then make and decorate your paper hat on the gallery floor! Suitable for all ages 11am ? 4pm Free. Just drop in Contact: 0161 474 2399

Easter Quiz, Bramall Park. All day, on 29 March 2013 ? 14 April 2013 Head to Bramall Hall for their Easter Quiz this holidays. Search for the chicks, scramble the clues and collect your treat. Suitable for children 4 ? 10 years and available during opening hours. Free with normal admission fee. Contact 0161 474 2020

Easter Mad Hatters Hat Party, Bramhall, on 30 March 2013 ? 30 March 2013 Come and join the FREE craft workshop and make your very own Easter hat to take home! 11am-3pm ? Village Square, Bramhall. Plus you can meet the Mad Hatter, Queen of Hearts and the Easter Bunny himself!

EASTER SUNDAY

Treacle Market ? Macclesfield, on 31 March 2013 ? 31 March 2013
The Easter Treacle Market is a quality Arts, Antiques,Crafts, Food and Drink Market held on the cobbles of the historic old Marketplace in Macclesfield.? With over? 100 stalls it stretches into Chestergate, Mill Street and Castle Street. Held on the last Sunday of every month from 10am-3pm.

Easter Eggstravaganza at Lyme Park, on 31 March 2013 ? 01 April 2013
Fabulous family trails, with a special Easter prize. Outdoor games, face painting and fun.? 11am-4pm House and Garden admission applies. NT members free admission, each trail adittional ?1. Last admission time: 4pm. Adult ?11 (House and garden admission), Child ?7 (House and garden admission), Family ?25 (House and garden admission)

Easter Weekend Special at The Miners Arms, Adlington ? Treasure Hunt & Easter Bonnet Competition, Quiz & Food.

The Grand Easter Festival, Bramall Park, 1100-1600, on 31 March 2013 ? 31 March 2013 Join us for a great family day out and special fundraising day organised by the ?Friends of Bramall Hall & Park?. A variety of side shows, stalls and activities in and around the Hall. A vintage bus, a display of hawks and owls, an Easter treasure hunt and much more. Looks set to be a fab family day out!. Suitable for all ages 11am ? 4pm Adults ?1.50, Children Free Just drop in. Contact: 0161 474 2020

SCHOOL HOLIDAYS ACTIVITIES & EVENTS

Easter Animal Craft, Hatworks, Stockport, on 02 April 2013 ? 04 April 2013
Make yourself an Easter chick, Bunny or Lamb at this fun crafts workshop. Suitable for ages 5 ? 11 10.30am ? 12 noon and 1pm ? 2.30pm ?3.50, Leisure Key ?3 Booking Essential Contact: 0161 474 2399

Easter Activity Days at Poynton Leisure Centre, on 02 April 2013 ? 12 April 2013
Poynton Leisure Centre provide Easter Holiday Activity Days for children aged 5-12 years. Mon-Fri 9am ? 5pm.?The morning session is 9am ? 12:30pm and the afternoon session is 1:30pm ? 5pm, with a supervised lunch in between.?There are limited spaces, so?book now to avoid disappointment. Full details here.

Easter Soccer Academy at Poynton Leisure Centre, on 02 April 2013 ? 05 April 2013
Soccer Academy provides fully supervised soccer coaching from qualified F.A. Coaches. Includes a goalkeeping coaching course.?Sessions will run each day from 9:00am ? 5pm For boys and girls aged 5 ? 10 years and 11 -14 years.?Full details and contact info here.

Everybody Learn to Swim Scheme Crash Courses at Poynton Leisure Centre, on 02 April 2013 ? 05 April 2013
Children can?either start swimming as a beginner or continue swimming as an improver on one of our 1 week intensive courses.?Courses include: Beginners; Stages 1, 2 & 3; Stages 4 & 6 and stroke development. This is for children aged?4 and above, each lesson lasts for 30 minutes. Full details and contact info here.?Prices start at ?16!

Little Book of Memories at Lyme Park, on 05 April 2013 ? 05 April 2013
Make an Edwardian scrap book, inspired by those at Lyme. 1-3pm All ages welcome. FREE activity, but garden admission applies, NT members free.

SCHOOL HOLIDAY EVENTS AT POYNTON LIBRARY

FREE Horrid Henry Creative Writing Work shop at Poynton Library, on 09 April 2013 ? 09 April 2013

FREE Horrid Henry story and activity afternoon at Poynton Library from 2-3pm. Join Explore Learning for a creative writing workshop (5-8 years). Book in advance 01625 374818

Easter Active Play at Poynton Library, on 11 April 2013 ? 11 April 2013

Easter Active Play?at Poynton Library from 10.30am (5-8 years). Book in advance 01625 374818, More details to follow.

Story teller Elizabeth Morris at Poynton Library, on 12 April 2013 ? 12 April 2013
Story teller Elizabeth Morris will weave wonderful stories of myths and legends from?10.30-11.15am. Tickets are ?3. Places for this Easter event will probably sell faster than hot cross buns, so book your place now. Contact the library on 01625 374818

Enjoy your Easter break.

Don?t forget we have a special Days Out Offer article, where you can get discounts off Knowsley Safari, Legoland, Stockley Farm and more. Click here

Source: http://www.mumsintheknow.co.uk/poynton/2013/03/28/easter-holidays-in-poynton/

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Friday, March 29, 2013

Florida school apologizes after students stomp on 'Jesus'

By Bruce Schreiner and Gilma Avalos , NBCMiami.com

Florida Gov. Rick Scott has waded into a religious-infused campus controversy, asking the state university system chancellor to look into a classroom lesson at Florida Atlantic University in which students were instructed to stomp on sheets of paper that had "Jesus" written on them.

Scott said in a letter Tuesday to State University System Chancellor Frank Brogan that he was "deeply disappointed" by the recent incident in an intercultural communications class and said it raised questions about "the lessons being taught in our classrooms." He said he wanted a report on the incident and how it was handled, as well as a statement of the university's policies to ensure such "lessons" don't occur again.

"As we enter the week memorializing the events of Christ's passion, this incident gave me great concern over the lessons we are teaching our students," Scott wrote in the letter.

A FAU spokeswoman told NBC 6 that the university received Scott's letter and appreciated his perspective.

"Florida Atlantic University is deeply sorry for any hurt that this incident may have caused the community and beyond," wrote Lisa Metcalf, the school's director of media relations, in an email. "As an institution of higher learning, we embrace open discourse in our classrooms, but with that comes a level of responsibility. The exercise was insensitive and hurtful; it will not be used again."

She added that lessons learned from the incident "will help us ensure our educational opportunities always reflect the university?s core values."

Youngest Bachelor's Graduate at FAU Gets Master's

Scott cited news reports indicating students were told by the class instructor to write "Jesus" in large letters on a sheet of paper and to place the paper on the floor in front of them. The students were given a brief time of reflection and then were told to step on the paper and tell the class how they felt.

The exercise has outraged religious leaders such as the Rev. Mark Boykin, who plans to lead a march from his Boca Raton church to FAU to condemn the assignment next week.

"We find this to be unconscionable, completely unprofessional and unacceptable," he said.

At least one student found it so unacceptable that he refused to participate. Ryan Rotela, a devout Mormon and a junior at FAU's Davie campus, claims he was punished for doing so.

His lawyer Hiram Sasser shared the notice of charges that Rotela received from FAU for violating the student code of conduct.

"You are requested to attend a Student Conduct Conference," the notice read.

"In the interim, you may not attend class (SPC 3710) or contact any of the students involved in this matter ? verbally or electronically ? or by any other means," the notice stated.

Dr. Charles Brown, FAU's senior vice president of student affairs, said that Rotela was never up for punishment for refusing to participate in the exercise, however.

"We apologize to all of our students and the community and people beyond the community who felt it was too sensitive," Brown said.

Scott applauded Rotela, whom he spoke with on Tuesday, "for having the courage to stand up for his faith."

"I told him that it took great conviction and bravery to stand up and say what he was asked to do was wrong, and went against what he believed in," Scott said in a statement.

Sasser said that Rotela is again in good standing with the university. He has re-enrolled in the class, but one that is being taught by a different professor.

Florida Gov. Scott to Universities: No More Tuition Hikes

State University System spokeswoman Kim Wilmath said officials would work closely with FAU in preparing a response to Gov. Scott's concerns.

"The State University System prides itself not only on its commitment to academic freedom, but at the same time, its awesome responsibility to the people it serves," she said in a written statement. "We are gratified to know that FAU has apologized for any offense the exercise has caused and has pledged never to use this exercise again. Clearly, there were things the university could have done differently by its own acknowledgement."

The governor didn't seem satisfied with the apology, saying it was "in many ways inconsequential to the larger issue of a professor's poor judgment."

"The professor's lesson was offensive, and even intolerant, to Christians and those of all faiths who deserve to be respected as Americans entitled to religious freedom," Scott said in his letter. "Our public higher educational institutions are designed to shape the minds of Florida's future leaders. We should provide educational leadership that is respectful of religious freedom of all people."

This story was originally published on

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2a0d3bc9/l/0Lusnews0Bnbcnews0N0C0Inews0C20A130C0A30C270C174850A0A70Eflorida0Eschool0Eapologizes0Eafter0Estudents0Estomp0Eon0Ejesus0Dlite/story01.htm

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Thursday, March 28, 2013

Obama says he's optimistic about immigration reform (Washington Bureau)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/295052819?client_source=feed&format=rss

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Brazilian doctor charged with 7 murders, may have killed 300, investigator says

By Anthony Boadle

BRASILIA (Reuters) - A Brazilian doctor who was charged with killing seven patients to free up beds at a hospital intensive care unit may have been responsible for as many as 300 deaths, according to a Health Ministry investigator.

Prosecutors said Dr. Virginia Soares de Souza and her medical team administered muscle relaxing drugs to patients, then reduced their oxygen supply, causing them to die of asphyxia at the Evangelical Hospital in the southern city of Curitiba.

De Souza, a 56-year-old widow, was arrested last month and charged with seven counts of aggravated first degree murder. Three other doctors, three nurses and a physiotherapist who worked under De Souza have also been charged with murder.

Prosecutors for the state of Parana said wiretaps of De Souza's phone conversations revealed that her motive was to free up hospital beds for other patients.

"I want to clear the intensive care unit. It's making me itch," she said in one recording released to Brazilian media. "Unfortunately, our mission is to be go-betweens on the springboard to the next life," she added in the same phone call.

De Souza's lawyer, Elias Mattar Assad, said investigators had misunderstood how an intensive care unit works and she would prove her innocence.

More cases are expected to emerge as investigators comb through 1,700 medical records of patients who died in the last seven years at the hospital, where De Souza headed the intensive care unit.

"We already have more than 20 cases established, and there are nearly 300 more that we are looking into," the chief investigator assigned by Brazil's Health Ministry, Dr. Mario Lobato, said on Globo TV's Fantastico program on Sunday.

If prosecutors prove that De Souza killed 300 patients, this could be one of the world's worst serial killings, rivaling the notorious case of Harold Shipman, the English doctor who was found to have killed at least 215 patients.

Lobato said the deaths he reviewed occurred under similar circumstances: a muscle relaxant such as Pancuronium (trademark Pavulon) was administered, increasing the patients' dependence on artificial respiration; then the oxygen supply was reduced, causing death by asphyxia.

Some of the patients were conscious moments before they died, he said.

Prosecutors said De Souza felt "all powerful" running the intensive care unit homicide, to the point where she "had the power to decree the moment when a victim would die."

In some cases, De Souza was absent from the hospital and gave instructions to end the life of a patient by telephone to members of her medical team, according to documents detailing the charges.

Last week, a Curitiba judge ordered the release of De Souza and her medical team. Prosecutors sought on Monday to have her returned to custody because she was the leader of the team and witnesses had reported being intimidated.

Parana state prosecutors asked police on Wednesday to investigate whether more hospital employees, including former managers, were involved in the case.

President Dilma Rousseff's government will announce steps on Thursday to reorganize the hospital, a spokesman for the Health Ministry said.

(Editing by Stacey Joyce)

Source: http://news.yahoo.com/brazilian-doctor-charged-7-murders-may-killed-300-225149812.html

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Outsourcing Telemarketing Services for Win Solution

For many small and medium sized businesses, outsourcing telemarketing services is an important and necessary step. ?If you don?t have the manpower or resources to handle telemarketing in house, outsourcing your telemarketing can free you and your employees to focus on the important, day to day operations of your business. ?Outsourcing telemarketing services turns over that job to those people who specialize in it. ?Outsourcing can also save your business some money. ?It?s a win/win situation, right?

Well, it is a good option for many businesses. ?However, don?t overlook the fact that outsourcing does require some maintenance on your part. ?Outsourcing telemarketing services is not just a matter of hiring a company and walking away. ?You will have to do some follow-up work along the way.

In order to hold up your end of the bargain as the outsourcer, these are some of the things that you must do:

  1. Prepare job information list.
    Provide the information that the telemarketing service needs to do its job. ?You will have to give them some basic information to get started with. ?Make sure that you give your name and contact number to the telemarketing service, even if you are just casually looking for information online. ?They are trying to develop new leads, just like you are.
  2. Tell them what you want.
    The telemarketing service cannot give you what you want from them if you do not make your needs explicitly clear. ?The importance of this point cannot be stressed enough. ?If you expect results from your telemarketing service, you must equip them to do their job by clearly outlining and defining what you expect from them. ?If you are looking for an increase in revenue, specifically state the number that you are looking for. ?If you want the telemarketing service to make a certain number of calls per day, say so. ?If you want a certain number of representatives to be assigned to your account, let them know. ?The most critical step in determining your outcome is clearly stating your goals and objectives.
  3. Learn where to get access to your results.
    Telemarketing services keep track of all sorts of statistics related to your campaign. ?They will prepare reports on things like total increase in revenue, number of calls made, the increase in sales by demographic, and sales by customer service representative. ?All the reports in the world don?t do you any good if you don?t know where or how to get them, though. ?Find out if the reports will be sent to you on a regular basis. Some companies give you access to their database so that you can check the reports whenever you wish. ?Whatever the system for relaying reports, you should know what you are signing up for.

When you outsource your telemarketing services, you can save a lot of time, stress and money. You just need to do a little bit of work at the outset and some periodic follow up. ?The clearer you are at the outset of your relationship, the better your results will be.

Let the expert team at Forlex Sales handle all of your outsourced telemarketing activities. Our team is highly trained to meet the needs of every business owner. In addition to telemarketing, we also offer application verification, lead generation, prospect research, rapid inquiry response, live real time transfers, market research, and everything else you need to grow your business.

Outsourcing Telemarketing Services
Forlex Sales was founded by a group of experts who specialize in marketing and information technology, so we understand how important it is to stay up to date with your information and your technology.

Contact us for?complimentary consultation?to make sure we are the best partner for your business.

?

Source: http://www.forlexsales.com/general-information/outsourcing-telemarketing-services/

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The hunt for a successor to lithium for bipolar disorder

The hunt for a successor to lithium for bipolar disorder [ Back to EurekAlert! ] Public release date: 27-Mar-2013
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body with an eye to developing a safer alternative. That's the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

Bethany Halford, C&EN senior editor, explains that lithium often is the first-line medication used to calm the highs and boost the lows of bipolar disorder, which affects about 9 million people at some point in their lives in the United States alone. Lithium has distinct advantages over the dozen or so other medications. For instance, lithium is the only medication proven effective in preventing suicide in the mania phase of bipolar disorder. Lithium also is inexpensive.

The article explains, however, that lithium also has drawbacks, with a fine line between the effective dose and the toxic dose. Side effects include thyroid problems, weight gain and, in some cases, kidney failure. In the hope of skirting lithium's limitations, scientists are trying to pinpoint exactly how lithium stabilizes mood and how it engenders those unwanted effects. The goal is development of a second-generation successor without lithium's downsides, and Halford describes how scientists are working to do so.

###

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.

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[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


The hunt for a successor to lithium for bipolar disorder [ Back to EurekAlert! ] Public release date: 27-Mar-2013
[ | E-mail | Share Share ]

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body with an eye to developing a safer alternative. That's the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

Bethany Halford, C&EN senior editor, explains that lithium often is the first-line medication used to calm the highs and boost the lows of bipolar disorder, which affects about 9 million people at some point in their lives in the United States alone. Lithium has distinct advantages over the dozen or so other medications. For instance, lithium is the only medication proven effective in preventing suicide in the mania phase of bipolar disorder. Lithium also is inexpensive.

The article explains, however, that lithium also has drawbacks, with a fine line between the effective dose and the toxic dose. Side effects include thyroid problems, weight gain and, in some cases, kidney failure. In the hope of skirting lithium's limitations, scientists are trying to pinpoint exactly how lithium stabilizes mood and how it engenders those unwanted effects. The goal is development of a second-generation successor without lithium's downsides, and Halford describes how scientists are working to do so.

###

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world's largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

To automatically receive news releases from the American Chemical Society, contact newsroom@acs.org.

Follow us: Twitter Facebook


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/acs-thf032713.php

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Quick View (for Android)


Quick View (free) for Andorid is the mobile companion to DigitalQuick, a service that allows you to easily encrypt files on your computer and on the file-syncing service Dropbox. DigitalQuick also allows you to control what other people can do with your secure documents, such as edit, copy, and print.

Though still in beta, DigitalQuick and Quick View offer a solution for individuals and businesses who want to take advantage of Dropbox's low cost and utility without compromising security. However, Digital Quick is quirky and the mobile app is no different. In my testing, Quick View lived up to its name: With it, you can quickly view secure files on the go?and little else.

Finding Files
Getting files into Digital Quick is a bit of a Byzantine process, requiring you to encrypt files on your computer and then move them on to your Android device via USB. Then, you fire up a file manager on your Android device (I use the Astro File Manager) and move the files into the My Documents directory inside the Quick View folder.

Did you have Quick View running while you did this? Well, you'll have to wait a full ten minutes before the app will sync with the DigitalQuick servers and update the permissions for the files you've moved. Until then, you'll see confusing error messages. There's no way to force the app to refresh, so you'll have restart the app, or move files into the Quick View directory before launching the app.

The Fassoo.com team has told me that future versions will include real-time permissions updating.

DigitalQuick's selling point is its support for Dropbox, and accessing your secure files from that service is straightforward with Quick View. Just tap the large Dropbox icon on the app's homescreen, tap allow on the next screen, and your DigitalQuick files (along with everything else in your Dropbox account) is available.

The process for linking Dropbox to DigitalQuick and adding encrypted files is covered in our review of the Web service.

Working With Quick View
Once you have access to your files, Quick View lets you view the contents without decrypting the files. Unfortunately, the built-in document viewer will not let you copy, edit, save, or really do anything with your documents.

You can decrypt files, removing all permissions and encryption, to share with users who aren't DigitalQuick users. Doing so, of course, defeats the purpose of using a document security system. You can also view the permissions assigned to a document, such as limitations on editing and printing. Unfortunately, you cannot change the permissions from the app?to do so, you'll have to login to the DigitalQuick website.

Quick View lets you share DigitalQuick documents via email, which is useful if your files are stored locally. Dropbox has more robust sharing options, though, which don't appear to affect the encryption or permissions of DigitalQuick documents. So you may be better off just sharing your documents through Dropbox directly.

Prior to publishing this review, DigitalQuick's developers informed us that an update allows users to import files directly from Dropbox without decrypting them and for users to access their local encrypted files without an Internet connection. These are welcome additions, but did not affect the score of the review.

Not for the Faint of Heart
If you're an avid DigitalQuick user already familiar with its quirks, using Quick View is a no brainer?despite all its drawbacks. If you're not a Digital Quick user, the app serves no purpose.

Because the service is still in beta, I don't want to be overly harsh, but users should be aware that Quick View is far from a finished product. The utility of being able to view and decrypt files is overshadowed by the difficulty in opening them, and the app lacks critical features like a built-in file manager and document editor. Though the app looks well-made it badly needs an improved user interface as the current version is difficult to use and completely un-intuitive. The included documentation did little to relieve my confusion.

The time has come for a service like DigitalQuick, but it and Quick View need to mature before they'll be ready to fill that niche.

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/fFoNMA6KU00/0,2817,2417151,00.asp

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